Tongue cancer

CANCER OF TONGUE

The eld of Tongue cancers are squamous cell carcinomas. These hap from the lining that covers the muscles of the tongue.

A malignant tumor arising from the epithelium that covers the tongue. The vast eld of tongue carcinomas are middling or poorly differentiated squamous cell carcinomas.

Squamous cell carcinoma of the tongue represents digit of the more ordinary malignancies encountered by the general otolaryngologist as well as by digit specializing in nous and cervix surgery. In the direction of the early lingual cancers, a wide variety of therapuetic options have been advocated in the literature, and in addition to planning the treatment of the primary neoplasm, direction of the cervix staleness be thoughtful as well.

PREDISPOSING FACTORS

All cancers of the head & neck exhibit a strong association with beverage consumption and baccy smoking, specially of cigarettes - in fact, baccy is intellection to be involved in well over 80% of cases of squamous radiophone carcinoma of the nous and neck. Chronic danger of the epithelial surfaces of the nous and cervix to these irritants are intellection to result in a "field cancerisation" sequence of hyperplasia, dysplasia and carcinoma. That is, the utilization of premalignant lesions haw then undergo malignant modify to become a cancer. Smoking and beverage act synergistically in the utilization of nous and cervix cancer - the venture when both of these factors is inform is more than double the venture of danger to one factor alone.

There is a dose-response relationship between danger to baccy smoking and the utilization of nous and cervix cancer - the more you smoke, the greater the risk. Smokers are up to 25 times more likely to amend nous and cervix cancer than their non-smoking counterparts. Passive smoking, baccy chewing and cigar smoking are also venture factors for the utilization of nous and cervix cancer. Up to the point of utilization of overt carcinoma, many of the changes related with cigarette smoking will alter if the patient quits smoking.

Alcohol consumptionas a venture factor for the utilization of nous and cervix cancer also shows a dose-response relationship - with heavy drinkers existence at greater risk. In addition, drinkers of spirits haw be at a greater venture than those who ingest wine.

Chronic viral infection is also related with the utilization of nous and cervix carcinoma. The Epstein-Barr Virus is strongly related with the utilization of nasopharyngeal cancer, whilst Human Papilloma Virus, Herpes Simplex Virus and Human Immunodeficieny Virus hit been related with the utilization of a number of different cancers of the nous and neck. This is intellection to be due to their interference with the function of tumour cistron genes and oncogenes.

Other venture factors allow immune deficient states (such as post solid-organ transplant); occupational exposures to agents such as asbestos and perchloroethylene; radiation; dietary factors; a genetic susceptibleness to the utilization of the disease; and poor test hygiene.

Cancers of the test cavity become with highest frequency in countries where the betel nut is chewed. With cancers of the lips, solarise danger is an added venture factor in development.