Sunday, June 5, 2011

Stomach cancer



Its a second most common malignancy in the world after lung cancer 



STOMACH CANCER 
Gastric cancer can develop in some part of the stomach and may distribute throughout the stomach and to other organs; particularly the esophagus, lungs, lymph nodes, and the liver. Stomach cancer causes about 800,000 deaths worldwide per year.

Stomach cancer is cancer that occurs in the breadbasket — the muscular sac located in the upper region of your abdomen, meet below your ribs. Your breadbasket is responsible for receiving and holding the matter you take and then serving to break down and foreshorten it.

Another term for breadbasket cancer is viscus cancer. These two terms most ofttimes refer to breadbasket cancer that begins in the mucus-producing cells on the inside covering of the breadbasket (adenocarcinoma). Adenocarcinoma is the most common type of breadbasket cancer.

Stomach cancer is exceptional in the United States, and the number of people diagnosed with the disease each assemblage is declining. Stomach cancer is much more common in another areas of the world, particularly Japan.

Cancers play in different sections of the breadbasket may cause different symptoms and run to have different outcomes. The location can also affect treatment options.

The breadbasket wall has 5 layers. As a cancer grows deeper into them, the prognosis (outlook) is not as good. The inner layer is the mucosa. This is where breadbasket acid and digestive enzymes are made, and where most breadbasket cancers start. Under this is a supporting layer titled the submucosa. This is surrounded by the muscularis, a layer of muscle that moves and mixes the breadbasket contents. The outmost 2 layers, the subserosa and the outermost serosa, behave as wrapping layers for the stomach.

Stomach cancers run to develop slowly over many years. Before a genuine cancer develops, pre-cancerous changes often occur in the lining of the stomach. These early changes rarely cause symptoms and therefore often go undetected.

CAUSES

When you're told that you hit Stomach cancer, it's natural to wonder what haw hit caused the disease. But no one knows the exact causes of breadbasket cancer. Doctors seldom know why one mortal develops breadbasket cancer and another doesn't.

Studies hit found the mass venture factors for breadbasket cancer:
Helicobacter pylori infection: H. pylori is a bacterium that commonly infects the intrinsic lining (the mucosa) of the stomach. Infection with H. pylori can cause breadbasket rousing and peptic ulcers. It also increases the venture of breadbasket cancer, but only a small number of infected grouping develop breadbasket cancer.

Long-term rousing of the stomach: People who hit conditions associated with long-term breadbasket rousing (such as the blood disease pernicious anemia) are at accumulated venture of breadbasket cancer. Also, grouping who hit had part of their breadbasket distant haw hit long-term breadbasket rousing and accumulated venture of breadbasket cancer some years after their surgery.

Smoking: Smokers are more likely than nonsmokers to develop breadbasket cancer. Heavy smokers are most at risk.

Family history: Close relatives (parents, brothers, sisters, or children) of a mortal with a history of breadbasket cancer are somewhat more likely to develop the disease themselves. If some near relatives hit a history of breadbasket cancer, the venture is even greater.

Poor diet, lack of physical activity, or obesity:
Studies suggest that grouping who eat a diet broad in foods that are smoked, salted, or pickled hit an accumulated venture for breadbasket cancer. On the other hand, grouping who eat a diet broad in fresh fruits and vegetables haw hit a lower venture of this disease.

A lack of physical state haw increase the venture of breadbasket cancer.
Also, grouping who are obese haw hit an accumulated venture of cancer developing in the upper part of the stomach.
On the other hand, grouping who do develop the disease sometimes hit no famous venture factors.



Stomach cancer treatment


TREATMENT
The communication of stomach cancer depends on the results of tests and your coverall health.

SURGERY

Surgery is the most common communication and is the exclusive wish of cure for breadbasket cancer. The surgeon removes conception or every of the stomach, as substantially as the surrounding lymph nodes, with the basic goal of removing every cancer and a margin of normal tissue. Depending on the extent of invasion and the positioning of the tumor, surgery may also allow remotion of conception of the intestine or pancreas. Tumors in the lower conception of the breadbasket may call for a Billroth I or Billroth II procedure. Endoscopic mucosal resection  is a communication for early gastric cancer that has been pioneered in Japan, but is also available in the United States at whatever centers. In this procedure, the tumor, together with the intrinsic lining of breadbasket (mucosa), is distant from the surround of the breadbasket using an electrical accommodate loop through the endoscope. The advantage is that it is a such smaller activeness than removing the stomach. Endoscopic submucosal dissection  is a similar technique pioneered in Japan, utilised to resect a large Atlantic of mucosa in one piece. If the pathologic examination of the resected specimen shows incomplete resection or deep invasion by tumor, the enduring would need a formal breadbasket resection.

CHEMOTHERAPY

The ingest of chemotherapy to impact breadbasket cancer has no established accepted of care. Unfortunately, breadbasket cancer has not been especially sensitive to these drugs until recently, and historically served to palliatively reduce the filler of the growth and process survival time. Some drugs utilised in breadbasket cancer communication include: fluorouracil, carmustine,  Semustine, and doxorubicin , as substantially as Mitomycin C, and more fresh cisplatin and taxotere in various combinations. The relative benefits of these drugs, alone and in combination, are unclear. Scientists are exploring the benefits of giving chemotherapy before surgery to shrink the tumor, or as adjuvant therapy after surgery to destroy remaining cancer cells. Combination communication with chemotherapy and radiation therapy is also under study. Doctors are testing a communication in which anticancer drugs are put directly into the abdomen (intraperitoneal hyperthermic chemoperfusion). Chemotherapy also is existence studied as a communication for cancer that has spread, and as a way to assuage symptoms of the disease. The side personalty of chemotherapy depend mainly on the drugs the enduring receives.

RADIATION THERAPY

Radiation therapy (also called radiotherapy) is the ingest of high-energy rays to damage cancer cells and kibosh them from growing. When used, it is generally in compounding with surgery and chemotherapy, or utilised exclusive with chemotherapy in cases where the individual is unable to undergo surgery. Radiation therapy may be utilised to assuage pain or blockage by shrinking the growth for palliation of incurable disease.


Stomach cancer diagnosis


Association with gastric cancer include blood group A and previous gastric surgery 



The breadbasket wall has 5 layers. As a cancer grows deeper into them, the prognosis (outlook) is not as good. The inner layer is the mucosa. This is where breadbasket acid and digestive enzymes are made, and where most breadbasket cancers start. Under this is a supporting layer titled the submucosa. This is surrounded by the muscularis, a layer of muscle that moves and mixes the breadbasket contents. The out most 2 layers, the subserosa and the outermost serosa, behave as wrapping layers for the stomach.

DIAGNOSIS

It is hard to study stomach cancer in its primeval stages. Indigestion and stomach discomfort can be symptoms of primeval cancer, but other problems can cause the same symptoms. In advanced cases, there may be blood in your stool, vomiting, unexplained weight loss, jaundice or pain swallowing.

ENDOSCOPY
This is the most common test utilised to diagnose cancer of the stomach. The endoscope is a thin, flexible plaything with a light and camera at the end. It is utilised to take photographs of the lining of the breadbasket and to take a small sample of cells (biopsy) to be examined under a microscope.

Sometimes the endoscopy plaything has an ultrasound probe at the end, which allows an ultrasound scan  to be done of the breadbasket and surrounding structures. This is famous as an endoscopic ultrasound.

BARIUM MEAL

This test will be done in the hospital x-ray department. It involves drinking a white, chalky liquefied (barium) which helps the gullet and breadbasket to show up on an x-ray.

These are X-rays of the esophagus, stomach, and first part of the intestine taken after the patient drinks a barium solution. The barium outlines the breadbasket on the X-ray, which helps the doctor, using special imaging equipment, to find tumors or other abnormal areas.

GASTROSCOPY AND BIOPSY

This test examines the esophagus and breadbasket using a thin, lighted plaything called a gastroscope, which is passed through the mouth to the stomach. Through the gastroscope, the student crapper look direct at the inside of the stomach. If an abnormal area is found, the student will remove whatever paper to be examined under a microscope. A biopsy is the exclusive trusty way to diagnose cancer. Gastroscopy and biopsy are the best methods of identifying breadbasket cancer.

HEMOGLOBIN ESTIMATION
Reveal anemia in 45% of cases.

TEST FOR OCCULT BLOOD IN THE STOOL

Stomach cancer symptoms


Eating smoked fish and highly spicy food have been implicated for stomach cancer
STOMACH CANCER SIGN AND SYMPTOMS

Stomach cancer is ofttimes asymptomatic or causes exclusive nonspecific symptoms in its early stages. By the instance symptoms occur, the cancer has ofttimes reached an advanced stage (see below), one of the main reasons for its poor prognosis. Stomach cancer can cause the following signs and symptoms:

EARLY
Indigestion or a executing sensation (heartburn)
Loss of appetite, especially for meat

LATE
Abdominal pain or discomfort in the bunk abdomen
Nausea and vomiting
Diarrhea or constipation
Bloating of the stomach after meals
Weight loss
weakness and fatigue
Bleeding (vomiting blood or having blood in the stool) which will materialize as black. This can lead to anemia.
Dysphagia; this feature suggests a growth in the cardia or extension of the gastric growth in to the esophagus.
These can be symptoms of another problems such as a stomach virus, gastric ulcer or tropical sprue and identification should be done by a gastroenterologist or an oncologist.

As the cancer grows, you may have other symptoms much as weight loss, regurgitation blood, or passing murder in faeces. This isn't commonly fresh, red blood, but dark blood. The murder expiration may go unnoticed, but over a punctuation of time, it can cause anaemia (when you have too few red murder cells or not sufficiency haemoglobin in your blood).
SPREAD

Stomach cancer crapper spread to different parts of the body. It crapper acquire through the wall of the stomach and into nearby meat or it crapper also spread to the lymph nodes and then through the lymph system.

When stomach cancer is more advanced, it will movement through the blood course and form deposits of cancer cells in meat such as the liver, lungs, and bones. But even though it has spread to another organs, it is still called stomach cancer. If it has spread in this manner, it crapper no longer be cured.

TYPES
There are three main types of breadbasket cancers: lymphomas, gastric stromal tumors, and carcinoid tumors. Lymphomas are cancers of the immune grouping tissue that are sometimes institute in the surround of the stomach. Gastric stromal tumors amend from the tissue of the breadbasket wall. Carcinoid tumors are tumors of hormone-producing cells of the stomach.