Monday, June 6, 2011

Thyroid cancer diagnosis


THE MEAN SURVIVAL RATE AFTER 10 YEARS IS HIGHER THAN 90% AND IS 100% IN VERY YOUNG PATIENTS WITH MINMAL OR NON METASTATIC DISEASE


THYROID CANCER DIAGNOSIS
DIAGNOSIS

After a enation is institute during a physical examination, a referral to an endocrinologist, a thyroidologist or specialist haw occur. Most commonly an ultrasound is performed to confirm the presence of a nodule, and set the status of the whole gland. Measurement of endocrine stimulating catecholamine and anti-thyroid antibodies module help end if there is a functional endocrine disease such as Hashimoto's thyroiditis present, a famous cause of a benign nodular goiter.

FINE NEEDLE BIOPSY

One approach used to watch whether the enation is malignant is the fine needle biopsy (FNB), which whatever have described as the most cost-effective, sensitive and accurate test.
FNB or ultrasound-guided FNA usually yields sufficient endocrine cells to set the venture of malignancy, although in whatever cases, the suspected enation haw need to be removed surgically for pathological examination.

BLOOD INVESTIGATION

Blood or imaging tests haw be done prior to or in lieu of a biopsy. The possibility of a enation which secretes endocrine catecholamine (which is less likely to be cancer) or hypothyroidism is investigated by measuring endocrine stimulating catecholamine (TSH), and the endocrine hormones thyroxine (T4) and triiodothyronine (T3).
Tests for humour endocrine autoantibodies are sometimes done as these haw indicate autoimmune endocrine disease (which crapper mimic nodular disease).

IMAGING
The blood assays haw be accompanied by ultrasound imaging of the enation to watch the position, size and texture, and to set whether the enation haw be cystic (fluid filled). Also suspicious findings in a enation are hypoechoic, product borders, microcalcifications, or rattling broad levels of murder line within the nodule. Less suspicious findings in benign nodules include, hyperechoic, comet tail artifacts from colloid, no murder line in the enation and a halo, or smooth border.
Some clinicians module also request technetium  or radioactive halogen imaging of the thyroid. An scan showing a blistering nodule, accompanied by a lower than connatural TSH, is strong grounds that the enation is not cancerous.




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