Cervical cancer treatment
Microinvasive carcinoma (stage IA) is usually treated by doing hysterectomy (removal of the uterus including all part of the vagina). Stage IA2, the lymph nodes removed. The option for patients who wish to remain fertile is a local surgical procedures, such as a cut-cycle procedure (LEEP) or cone biopsy. If the cone biopsy does not produce clear margins, possible treatment option for patients who wish to preserve fertility is trachelectomy.This trying to surgically remove the tumor while preserving the ovaries and uterus, providing the operation is more prudent hysterectomy.It a viable option for those with stage I cervical cancer has not spread, but is not yet considered standard of care, as few doctors are skilled in this procedure.Even most experienced surgeon can not promise that a trachelectomy can be done only after surgical microscopic examination of the extent of cancer spread.
If there is surgeon is not able to do microscopically confirm clear link of cervical tissue once the patient is under general anesthesia ( GA ) in the theater ( operating room ), a hysterectomy may still be necessary. This can be done under the same operation if the patient has given consent. Because of the possible risk of cancer spread to lymph nodes in step 1b cancers and some stage 1a cancers, the surgeon may also need to remove some lymph nodes in the uterus in the pathological evaluation.
A radical trachelectomy may be done abdominal or vaginal are differing opinions on what is better.A radical trachelectomy with abdominal lymph nodes, usually only two or three days in hospital, and most women can recover very quickly (approximately in six weeks). Complications are rare, even women who think they know after surgery are susceptible to preterm labor and possible late miscarriage. It is generally recommended to wait at least a year before trying to conceive after cervical surgery.Recurrence remaining is very rare if the cancer was removed trachelectomy.
Nevertheless, it is recommended for patients to practice vigilant prevention and follow-up care, including pap test / colposcopy, and with biopsies of the remaining segment of the uterus below as needed ( every 3 to 4 months for at least five years ) to monitor for any recurrence in addition to minimize exposure to HPV through new safe sex until you actively trying to conceive. Early stages (IB1 and IIA less than 4 cm) may be treated with radical hysterectomy with lymph node removal or radiation. Radiotherapy is given to external beam radiotherapy to the pelvis and brachytherapy (internal radiation). Patients treated with surgery who have high risk features found on pathologic examination are given radiation therapy with or without chemotherapy to reduce the risk of relapse.
The largest early-stage tumors (IB2 and IIA more than 4 cm) can be treated with radiotherapy and cisplatin chemotherapy, hysterectomy (which then usually requires adjuvant radiation therapy) or cisplatin chemotherapy after hysterectomy. Advanced tumors (IIB-IVA) were treated with radiotherapy and cisplatin-based chemotherapy. 15. June 2006, the U.S. Food and Drug Administration approved the use of two chemotherapy drugs, cisplatin and final women's HYCAMTIN (IVB) cervical cancer. Combination therapy is a significant risk of neutropenia, anemia and thrombocytopenia side effects. HYCAMTIN is manufactured by GlaxoSmithKline.
No comments:
Post a Comment