Sunday, May 29, 2011

Vaccination for cervical cancer


Primary Prevention  through Vaccination

Gardasil, manufactured under license by Merck & Co. is a vaccine against HPV types 6, 11, 16 and 18. Gardasil is effective up to 98%. It has been received approval from the Food and Drug Administration of 08 June  in 2006. Gardasil was approved in the EU. Cervarix, made by GlaxoSmithKline, was set to 92% effective in prevention of HPV strains 16 and 18  and is effective for more than 4 years. Cervarix was approved in October 16, 2009 United States and the EU in September of 2007, and in other nations. Neither Merck & Co., and GlaxoSmithKline have invented the vaccine. The key stages of vaccine development are claimed by the National Cancer Institute in the United States, the University of Rochester in New York, Georgetown University in Washington, DC, Dartmouth College, Hanover, NH, and the University of Queensland in Brisbane, Australia. Both Merck & Co. and GlaxoSmithKline have licensed patents of all parties.

Together, the types of HPV 16 and 18 currently cause about 70% of cervical cancers. HPV types 6 and 11can cause about 90% of genital wart cases. HPV vaccines have also been shown to prevent the precursors of some other types of cancer by HPV. HPV vaccines are aimed at girls and women ages 9-26, because the vaccine only works if given before infection occurs, and therefore in the public health workers are bound to girls before they begin having sex. The vaccines have been shown to be effective for at least 4-6 years, and is believed to be effective for longer, but the duration of effectiveness, and if a booster is needed is unknown. Men use of the vaccine to prevent genital warts, anal cancer, and to suspend transmission to women or other men must first be considered only on the secondary market. the high cost of this vaccine is a cause for concern. Several countries have or are considering programs to fund the HPV vaccine

Vaccines for cervical cancer are aimed at girls and women ages 9 - 26 ,because only it works if given before infection occurs .And  vaccine affective for atleast 4 - 6 years .



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